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CPT · 12% of the exam

Special Collections practice questions

10 free Special Collections questions for the Certified Phlebotomy Technician (CPT) exam, each with the correct answer and an explanation for every option.

What this domain covers

Collections beyond routine draws: blood cultures, timed tests, point-of-care testing and special handling.

Exam weight
12%
On a real exam
≈ 14 questions
In our bank
73 questions

Topics that come up most

  • Blood culture collection
  • Timed and fasting tests
  • Glucose tolerance testing
  • Point-of-care testing
  • Chain-of-custody collections

How to study it

Learn the special steps for each test type; distractors are routine-draw steps applied to the wrong test.

Sample Special Collections questions

Try each one before opening the answer. Original questions written to the official exam objectives.

  1. Question 1

    A phlebotomist is collecting a specimen for a type and crossmatch before a transfusion. Which labeling practice is required?

    • ALabel the tubes at the bedside right after the draw, matching two identifiers to the wristband
    • BPre-label the tubes at the nurses' station before entering the room to save time
    • CDraw and label the tubes using only the name the patient states when the wristband is missing
    • DLabel the tubes in the laboratory after all specimens from the unit have been gathered
    Show answer and explanation

    Answer: A) Label the tubes at the bedside right after the draw, matching two identifiers to the wristband

    Most hemolytic transfusion reactions come from misidentified patients or mislabeled samples. Blood bank tubes must be labeled at the bedside right after collection, using identifiers that match the patient's wristband.

    • ACorrect. Pretransfusion specimens are labeled immediately at the bedside after collection. The label must match the wristband's unique identifiers, such as full name and medical record number.
    • BIncorrect. Labeling tubes before collection risks putting another patient's blood in a labeled tube. Labeling errors are a leading cause of hemolytic transfusion reactions.
    • CIncorrect. Patient identity must be verified against the wristband. A stated name alone is not acceptable for blood bank specimens.
    • DIncorrect. Labeling away from the patient breaks positive identification and invites mix-ups. Tubes must be labeled at the bedside.
  2. Question 2

    Where is the swab placed for a nasopharyngeal specimen?

    • AJust inside the nostril tip
    • BInto the mouth, to the tonsils
    • CDeep through the nostril
    • DInto the ear canal
    Show answer and explanation

    Answer: C) Deep through the nostril

    • AIncorrect. That is an anterior nasal swab, not nasopharyngeal.
    • BIncorrect. That is a throat swab.
    • CCorrect. The swab goes through the nostril to the back of the nasal passage.
    • DIncorrect. The ear is not used for this specimen.
  3. Question 3

    When collecting a newborn screening card, what should be avoided?

    • ALetting the card dry
    • BUsing a heel stick
    • CFilling every circle
    • DTouching the circles
    Show answer and explanation

    Answer: D) Touching the circles

    • AIncorrect. Cards must dry fully before shipping.
    • BIncorrect. Heel sticks are standard for newborn screening.
    • CIncorrect. Every circle should be filled.
    • DCorrect. Fingers or gloves can contaminate the paper.
  4. Question 4

    Therapeutic phlebotomy, the removal of blood as treatment, is used for conditions such as:

    • ADehydration
    • BIron-deficiency anemia and low blood volume
    • CHemophilia
    • DHemochromatosis and polycythemia
    Show answer and explanation

    Answer: D) Hemochromatosis and polycythemia

    • AIncorrect. That needs fluid replacement.
    • BIncorrect. Removing blood would worsen anemia.
    • CIncorrect. That's a clotting disorder.
    • DCorrect. It lowers iron or red cell levels.
  5. Question 5

    A yellow-top SPS tube is used for:

    • ABlood cultures, when bottles aren't used
    • BGlucose
    • CCoagulation studies such as PT and PTT on citrated plasma
    • DLead testing
    Show answer and explanation

    Answer: A) Blood cultures, when bottles aren't used

    • ACorrect. SPS helps preserve bacteria.
    • BIncorrect. That's gray.
    • CIncorrect. That's light blue.
    • DIncorrect. That's tan or royal blue.
  6. Question 6

    Which check is part of screening a blood donor before collection?

    • AHemoglobin level
    • BBlood alcohol level
    • CUrine drug screen
    • DCholesterol panel
    Show answer and explanation

    Answer: A) Hemoglobin level

    • ACorrect. Donors are screened for adequate hemoglobin or hematocrit, along with weight and health history.
    • BIncorrect. This is not a standard donor screen.
    • CIncorrect. This is not a standard donor screen.
    • DIncorrect. This is not a donor screening requirement.
  7. Question 7

    A creatinine clearance test typically requires:

    • AOnly a throat swab
    • BA timed urine collection plus a blood creatinine
    • COnly a random urine sample collected at any time
    • DA blood culture
    Show answer and explanation

    Answer: B) A timed urine collection plus a blood creatinine

    • AIncorrect. It uses urine and blood.
    • BCorrect. Both are needed to calculate clearance.
    • CIncorrect. A timed urine and blood are used.
    • DIncorrect. It uses urine and blood creatinine.
  8. Question 8

    Paternity testing samples require:

    • AStrict ID and chain-of-custody records
    • BNo identification
    • CFasting for 12 hours before the collection
    • DA gray-top tube
    Show answer and explanation

    Answer: A) Strict ID and chain-of-custody records

    • ACorrect. Results may be used legally.
    • BIncorrect. Identity must be verified.
    • CIncorrect. Fasting isn't needed.
    • DIncorrect. Collection follows the testing lab's kit.
  9. Question 9

    A patient has finished the glucose drink for an oral glucose tolerance test and is waiting for the next timed draw. Which instruction should the phlebotomist give?

    • AStay seated in the waiting area and do not eat or smoke until the test is finished
    • BWalk around the facility between draws to help the body process the glucose load
    • CDrink a small glass of juice if they feel lightheaded before the next scheduled draw
    • DLeave and run errands, as long as they return on time for each draw and keep fasting
    Show answer and explanation

    Answer: A) Stay seated in the waiting area and do not eat or smoke until the test is finished

    During an OGTT the patient must not eat. They should also stay seated and avoid smoking and physical activity between timed draws, because these change blood glucose and would distort the results.

    • ACorrect. The patient cannot eat during the test. Physical activity and smoking also change glucose levels, so the patient should rest quietly and stay on site for every timed draw.
    • BIncorrect. Walking is physical activity, and muscle activity lowers blood glucose. That would make the timed results look falsely normal.
    • CIncorrect. Juice adds sugar and invalidates the test. If the patient has symptoms, the phlebotomist should notify the provider rather than give food or drink.
    • DIncorrect. Activity away from the facility can't be controlled and changes glucose levels, so the patient should stay seated on site until the last draw.
  10. Question 10

    How should a newborn screening filter paper card be dried?

    • AStacked with other cards
    • BIn direct sunlight
    • CFlat and unstacked
    • DWith a hair dryer
    Show answer and explanation

    Answer: C) Flat and unstacked

    • AIncorrect. Stacking causes cross-contamination.
    • BIncorrect. Sunlight can damage the sample.
    • CCorrect. Cards dry flat for several hours, away from heat and sunlight, without touching other cards.
    • DIncorrect. Heat can damage the sample.

Special Collections: FAQs

How much of the CPT exam is Special Collections?

Special Collections is 12% of the CPT exam by the official exam guide's weighting, which on a 120-question form works out to roughly 14 questions. The real exam's exact split varies by form.

What does the Special Collections domain cover?

Collections beyond routine draws: blood cultures, timed tests, point-of-care testing and special handling.

How should I study Special Collections for CPT?

Learn the special steps for each test type; distractors are routine-draw steps applied to the wrong test.

Where can I practise more Special Collections questions?

This page has 10 free Special Collections questions with answers. The ExamWize CPT question bank has 73 questions in this domain. Every practice exam result breaks your score down by domain, and Review Mode re-drills the questions you missed.

Get Special Collections exam-ready

The full CPT bank has 73 Special Collections questions. Timed practice exams match the real exam's length and domain weights, every result shows your score per domain, and Review Mode re-drills the questions you missed.

Not affiliated with NHA; questions are original, written from the official exam outline, and never copied from the real exam.