Skip to main content

NHA · CPT

CPT Phlebotomy Technician practice questions with answers

15 free practice questions for the Certified Phlebotomy Technician (CPT), spread across the exam's topics. Try each one, then open the answer to see why every option is right or wrong.

  1. Question 1 · Safety and Compliance

    The main purpose of an incident report is to:

    • ABill the patient for the incident
    • BPunish the employee involved and record the penalty given
    • CDocument events so the facility can improve safety
    • DReplace the patient's chart entry
    Show answer and explanation

    Answer: C) Document events so the facility can improve safety

    • AIncorrect. It's for documentation and improvement.
    • BIncorrect. It's for improvement.
    • CCorrect. It isn't meant as a disciplinary record.
    • DIncorrect. It's a separate internal record.
  2. Question 2 · Safety and Compliance

    Why is the saying 'if it wasn't documented, it wasn't done' important?

    • AUndocumented actions may be treated as not done
    • BIt saves paper
    • CDocumentation is optional
    • DIt applies only to billing records, not patient care
    Show answer and explanation

    Answer: A) Undocumented actions may be treated as not done

    • ACorrect. Accurate records protect patients and staff.
    • BIncorrect. It concerns legal proof.
    • CIncorrect. It's required.
    • DIncorrect. It applies to all care.
  3. Question 3 · Safety and Compliance

    During the scheduled function check, a phlebotomist finds that the lab's centrifuge speed is outside the manufacturer's acceptable limits. What should the phlebotomist do?

    • ATake the centrifuge out of service, document and report the failed check, and spin patient specimens in a centrifuge that has passed its checks
    • BKeep using the centrifuge but lengthen the spin time for each run to make up for the lower speed until a technician arrives
    • CKeep using the centrifuge as long as serum and plasma still look visibly separated from the cells after each run
    • DRecord the reading in the maintenance log and keep using the centrifuge until its next scheduled preventive maintenance
    Show answer and explanation

    Answer: A) Take the centrifuge out of service, document and report the failed check, and spin patient specimens in a centrifuge that has passed its checks

    Lab equipment such as centrifuges must pass documented maintenance and function checks within the manufacturer's limits before patient specimens are processed. A unit that fails should be removed from service, and the failure documented and reported.

    • ACorrect. CLIA requires function checks to be within the manufacturer's limits before patient testing, and maintenance and function checks must be documented. An out-of-limit centrifuge could separate specimens poorly or fail mechanically, so it must not be used until it is repaired and passes its checks again.
    • BIncorrect. Changing spin time to make up for a failed check is not a validated procedure and does not correct the problem. Equipment that fails its function check should not be used for patient specimens.
    • CIncorrect. Visual separation does not confirm correct speed or force. Incomplete separation or cell damage may not be visible and can affect test results. The check must be within limits before patient use.
    • DIncorrect. Documenting the failure is required, but it is not enough. The centrifuge must be removed from patient use until it is serviced and passes its function check.
  4. Question 4 · Safety and Compliance

    After completing the hepatitis B vaccine series, a phlebotomist may have a titer drawn to:

    • ACheck blood type
    • BDetect HIV
    • CConfirm immunity
    • DMeasure blood sugar
    Show answer and explanation

    Answer: C) Confirm immunity

    • AIncorrect. It measures hepatitis B antibodies.
    • BIncorrect. It measures hepatitis B antibodies.
    • CCorrect. A positive antibody level shows protection.
    • DIncorrect. It measures hepatitis B antibodies.
  5. Question 5 · Patient Preparation

    During pregnancy, increased plasma volume can cause:

    • ANo change in blood values
    • BHigher hematocrit
    • CLower hematocrit from hemodilution
    • DA change in blood type
    Show answer and explanation

    Answer: C) Lower hematocrit from hemodilution

    • AIncorrect. Values can change.
    • BIncorrect. Plasma volume rises more than red cells.
    • CCorrect. Pregnancy reference ranges may differ.
    • DIncorrect. Blood type doesn't change.
  6. Question 6 · Patient Preparation

    Compared with adults, healthy newborns usually have:

    • ANo red blood cells
    • BLower hemoglobin and fewer red cells than adults
    • CHigher hemoglobin and red cell counts
    • DIdentical blood values
    Show answer and explanation

    Answer: C) Higher hemoglobin and red cell counts

    • AIncorrect. Newborn values are higher.
    • BIncorrect. Newborn values are higher.
    • CCorrect. Values fall during the first months.
    • DIncorrect. Newborn values differ.
  7. Question 7 · Patient Preparation

    A dialysis patient has an arteriovenous (AV) fistula in one arm. What should the phlebotomist do?

    • AAvoid that arm
    • BUse the fistula for an easy draw
    • CApply the tourniquet over the fistula
    • DDraw from either arm
    Show answer and explanation

    Answer: A) Avoid that arm

    • ACorrect. An arm with an AV fistula must not be used for venipuncture.
    • BIncorrect. Using the fistula can damage the patient's dialysis access.
    • CIncorrect. Pressure can damage the fistula.
    • DIncorrect. The fistula arm must be avoided.
  8. Question 8 · Routine Blood Collections

    The vein rolls away when the needle approaches. What helps?

    • ARemove the tourniquet first
    • BInsert the needle more slowly
    • CAnchor the vein more firmly
    • DPush harder on the vein above
    Show answer and explanation

    Answer: C) Anchor the vein more firmly

    • AIncorrect. The tourniquet helps the vein stay visible.
    • BIncorrect. Slow insertion lets the vein roll more.
    • CCorrect. Pulling the skin taut below the site holds the vein in place.
    • DIncorrect. Pressing above can collapse the vein.
  9. Question 9 · Routine Blood Collections

    How should the needle be withdrawn from the vein?

    • AWhile pressing hard on it
    • BQuickly, while twisting
    • CSmoothly, same angle
    • DIn several small jerks
    Show answer and explanation

    Answer: C) Smoothly, same angle

    • AIncorrect. Press only after the needle is out.
    • BIncorrect. Twisting damages tissue.
    • CCorrect. A smooth withdrawal at the same angle reduces tissue damage.
    • DIncorrect. Jerky motion causes injury.
  10. Question 10 · Routine Blood Collections

    If EDTA carries over into a chemistry tube, what can happen?

    • AThere is no effect
    • BGlucose rises sharply in the tube
    • CThe tube turns blue
    • DPotassium reads falsely high
    Show answer and explanation

    Answer: D) Potassium reads falsely high

    • AIncorrect. EDTA carryover can alter results.
    • BIncorrect. EDTA carryover mainly affects potassium and calcium.
    • CIncorrect. Tubes do not change color.
    • DCorrect. EDTA contains potassium and binds calcium, so it can raise potassium and lower calcium results.
  11. Question 11 · Routine Blood Collections

    While changing tubes during a draw, the phlebotomist should:

    • ARelease the needle completely
    • BPull the needle back slightly each time a tube is changed
    • CHold the holder steady so the needle doesn't move
    • DPush the needle deeper each time
    Show answer and explanation

    Answer: C) Hold the holder steady so the needle doesn't move

    • AIncorrect. Keep a steady hold.
    • BIncorrect. Keep it steady.
    • CCorrect. Movement can cause pain or a hematoma.
    • DIncorrect. Keep it steady.
  12. Question 12 · Special Collections

    When collecting blood cultures with a winged (butterfly) set, which bottle is usually filled first?

    • AThe aerobic bottle
    • BThe anaerobic bottle
    • CA lavender tube
    • DEither one; order never matters
    Show answer and explanation

    Answer: A) The aerobic bottle

    • ACorrect. With a butterfly, the aerobic bottle goes first so tubing air enters it, not the anaerobic bottle.
    • BIncorrect. Air from the tubing would enter the anaerobic bottle.
    • CIncorrect. Blood cultures are drawn before other tubes.
    • DIncorrect. Bottle order matters with a winged set.
  13. Question 13 · Special Collections

    A collector is preparing a donor for a chain-of-custody urine drug screen. Which instruction should the collector give the donor before the donor enters the restroom?

    • AEmpty all pockets and show the collector the items in them
    • BDrink several glasses of water so the sample is easier to provide
    • CKeep a purse or bag in the restroom so belongings stay secure
    • DFlush the toilet before handing the specimen to the collector
    Show answer and explanation

    Answer: A) Empty all pockets and show the collector the items in them

    Before a chain-of-custody drug screen, the donor empties their pockets and shows the contents, takes off outer garments, and leaves personal belongings outside the restroom. This keeps anything that could be used to tamper with the specimen out of the collection area.

    • ACorrect. Federal collection procedures require the donor to empty their pockets and show the contents, so nothing that could adulterate or substitute the specimen is brought into the collection site.
    • BIncorrect. Drinking extra fluid before collection can dilute the specimen. The donor is not told to hydrate beforehand.
    • CIncorrect. Personal belongings such as a purse or briefcase stay with the collector or in an agreed location, because they could be used to hide adulterants.
    • DIncorrect. The donor is told not to flush. Water sources are secured so the specimen cannot be diluted or substituted.
  14. Question 14 · Processing

    About what share of whole blood volume is plasma?

    • AAbout 25%
    • BAbout 5%
    • CAbout 55%
    • DAbout 95%
    Show answer and explanation

    Answer: C) About 55%

    • AIncorrect. This is too low.
    • BIncorrect. Plasma is the largest part of blood.
    • CCorrect. Plasma is roughly 55% of blood; cells make up about 45%.
    • DIncorrect. Cells make up a large share of blood too.
  15. Question 15 · Processing

    In a hospital laboratory, which computer system is used to enter test orders, assign specimen accession numbers, and look up a specimen's status from receipt through result reporting?

    • ALaboratory information system (LIS)
    • BPicture archiving and communication system (PACS)
    • CPractice management (billing) system
    • DPharmacy information system
    Show answer and explanation

    Answer: A) Laboratory information system (LIS)

    The laboratory information system (LIS) is where specimen orders are entered, accession numbers are assigned, and specimens are tracked through to result reporting.

    • ACorrect. The LIS logs and tracks specimens and their accession numbers, manages workflow, and reports results to providers.
    • BIncorrect. PACS stores and displays medical images such as X-rays and CT scans. It does not track laboratory specimens.
    • CIncorrect. A practice management system handles scheduling, registration and billing. It does not accession or track specimens through testing.
    • DIncorrect. A pharmacy system manages medication orders and dispensing, not laboratory specimens.

Ready for a full CPT practice exam?

These are a sample from the ExamWize question bank. Full practice exams match the real exam's length, time limit and topic weights, with every answer explained.

Original questions written from the official exam outline. Not affiliated with NHA; never copied from the real exam.