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PTCE · 35% of the exam

Medications practice questions

10 free Medications questions for the Pharmacy Technician Certification Exam (PTCE) exam, each with the correct answer and an explanation for every option.

What this domain covers

The largest PTCE domain: brand and generic names, therapeutic classes, dosage forms and the safety information a technician must recognise.

Exam weight
35%
On a real exam
≈ 32 questions
In our bank
207 questions

Topics that come up most

  • Brand and generic names of commonly dispensed drugs
  • Therapeutic classes and common indications
  • Dosage forms, strengths and routes
  • Drug interactions and contraindications
  • Storage requirements and stability

How to study it

Learn the top 200 drugs by class rather than alphabetically; questions often ask which drug belongs with which class or indication.

Sample Medications questions

Try each one before opening the answer. Original questions written to the official exam objectives.

  1. Question 1

    A prescription reads "Prozac 20 mg capsules, take 1 daily" and generic substitution is permitted. Which product should the technician select from the shelf?

    • ASertraline 20 mg
    • BFluoxetine 20 mg capsules
    • CParoxetine 20 mg tablets
    • DDuloxetine 20 mg capsules
    Show answer and explanation

    Answer: B) Fluoxetine 20 mg capsules

    Prozac is the brand name for fluoxetine, an SSRI. When generic substitution is allowed, fluoxetine is the correct product.

    • AIncorrect. Sertraline is the generic for Zoloft, a different SSRI, not Prozac.
    • BCorrect. Fluoxetine is the generic name for Prozac, a selective serotonin reuptake inhibitor (SSRI).
    • CIncorrect. Paroxetine is the generic for Paxil, a different SSRI.
    • DIncorrect. Duloxetine is the generic for Cymbalta, an SNRI, not Prozac.
  2. Question 2

    What is the generic name of Nexium?

    • ARabeprazole
    • BOmeprazole
    • CEsomeprazole
    • DRanitidine
    Show answer and explanation

    Answer: C) Esomeprazole

    • AIncorrect. Rabeprazole is sold as Aciphex.
    • BIncorrect. Omeprazole is sold as Prilosec.
    • CCorrect. Nexium is esomeprazole, a proton pump inhibitor.
    • DIncorrect. Ranitidine was an H2 blocker sold as Zantac.
  3. Question 3

    What is the generic name of Effexor XR?

    • AEscitalopram
    • BDuloxetine
    • CBupropion
    • DVenlafaxine
    Show answer and explanation

    Answer: D) Venlafaxine

    • AIncorrect. Escitalopram is Lexapro.
    • BIncorrect. Duloxetine is Cymbalta.
    • CIncorrect. Bupropion is Wellbutrin.
    • DCorrect. It's an SNRI antidepressant.
  4. Question 4

    Tacrolimus is mainly used to:

    • ARelieve pain
    • BTreat bacterial infections
    • CLower blood pressure
    • DPrevent organ transplant rejection
    Show answer and explanation

    Answer: D) Prevent organ transplant rejection

    • AIncorrect. It's an immunosuppressant.
    • BIncorrect. It's an immunosuppressant.
    • CIncorrect. It's an immunosuppressant.
    • DCorrect. It's an immunosuppressant with blood level monitoring.
  5. Question 5

    Why must sildenafil not be taken with nitrates such as nitroglycerin?

    • AThe nitrate stops working completely
    • BIt can cause severe high blood sugar
    • CIt raises the risk of kidney stones
    • DIt can make blood pressure drop too low
    Show answer and explanation

    Answer: D) It can make blood pressure drop too low

    • AIncorrect. The danger is a dangerous drop in blood pressure, not lost effect.
    • BIncorrect. Blood sugar is not the concern with this combination.
    • CIncorrect. Kidney stones are not the concern with this combination.
    • DCorrect. Both drugs widen blood vessels, and together they can cause severe hypotension.
  6. Question 6

    For an outpatient with uncomplicated influenza, when does oseltamivir (Tamiflu) give the greatest clinical benefit?

    • AWhen it is started 5 to 7 days after onset, once viral levels peak
    • BWhen it is started as soon as possible, ideally within 48 hours of onset
    • CWhen it is started only after a fever has lasted at least 72 hours
    • DWhen it is started after over-the-counter cold remedies fail to help
    Show answer and explanation

    Answer: B) When it is started as soon as possible, ideally within 48 hours of onset

    CDC says influenza antivirals like oseltamivir help most when started as soon as possible, ideally within 48 hours of symptom onset. Some later starts can still help hospitalized or severely ill patients.

    • AIncorrect. CDC says the benefit is greatest when treatment starts early, not after the illness is well established.
    • BCorrect. CDC says to start antiviral treatment as soon as possible after illness onset, ideally within 48 hours of symptom onset, for the greatest clinical benefit.
    • CIncorrect. Waiting for a fever to last several days pushes treatment past the window where it helps most.
    • DIncorrect. Trying other products first only delays treatment. Oseltamivir works best when it's started early.
  7. Question 7

    How should pharmacy stock of unopened multi-dose latanoprost eye drop bottles be stored before dispensing?

    • AIn the freezer until the day of dispensing
    • BIn the refrigerator until dispensed
    • CAt room temperature on the shelf with other eye drops
    • DAt room temperature in a dark cabinet, away from light
    Show answer and explanation

    Answer: B) In the refrigerator until dispensed

    Unopened multi-dose latanoprost bottles are kept in the refrigerator. After opening, they may be kept at room temperature for up to 6 weeks.

    • AIncorrect. Unopened latanoprost bottles go in the refrigerator, not the freezer. Freezing isn't part of the storage directions.
    • BCorrect. Unopened multi-dose latanoprost bottles are refrigerated. After opening, the patient may keep the bottle at room temperature for up to 6 weeks.
    • CIncorrect. Room temperature is allowed only after the multi-dose bottle is opened, and only for a limited time. Unopened stock must be refrigerated.
    • DIncorrect. Keeping the bottle away from light doesn't replace refrigeration. Unopened multi-dose bottles must still be kept in the refrigerator.
  8. Question 8

    A technician is filling a prescription for prednisone 10 mg tablets with tapering directions. To which drug class does prednisone belong?

    • ANonsteroidal anti-inflammatory drug (NSAID)
    • BAntihistamine
    • CHistamine-2 (H2) blocker
    • DCorticosteroid
    Show answer and explanation

    Answer: D) Corticosteroid

    Prednisone is a systemic corticosteroid used to reduce inflammation and suppress the immune response.

    • AIncorrect. NSAIDs such as ibuprofen and naproxen reduce inflammation without being steroids. Prednisone is a steroid.
    • BIncorrect. Antihistamines such as cetirizine block histamine receptors. Prednisone does not work this way.
    • CIncorrect. H2 blockers such as famotidine reduce stomach acid. They are not used to treat inflammation.
    • DCorrect. MedlinePlus lists prednisone as a corticosteroid. It reduces inflammation and changes how the immune system responds, and long courses are often tapered.
  9. Question 9

    A patient received ketorolac injections in the hospital and is being discharged on oral ketorolac tablets. The combined duration of all ketorolac therapy (injection plus oral) must not exceed:

    • A3 days
    • B5 days
    • C10 days
    • D14 days
    Show answer and explanation

    Answer: B) 5 days

    All ketorolac therapy, IV/IM plus oral, is limited to 5 days in total. Oral ketorolac must be stopped by the fifth day after the first injection.

    • AIncorrect. The total limit for ketorolac therapy, injection and oral combined, is 5 days, not 3.
    • BCorrect. Ketorolac is for short-term relief of moderately severe pain, and total use, including any IV/IM doses, must not go beyond 5 days because of the risk of bleeding, kidney and other serious adverse effects.
    • CIncorrect. 10 days is twice the allowed total. Ketorolac therapy is limited to 5 days combined.
    • DIncorrect. Ketorolac is not meant for a two-week course. The total limit is 5 days.
  10. Question 10

    Bactrim contains which drugs?

    • ASulfamethoxazole and trimethoprim
    • BAmoxicillin and clavulanate
    • CCiprofloxacin and dexamethasone
    • DErythromycin and sulfisoxazole
    Show answer and explanation

    Answer: A) Sulfamethoxazole and trimethoprim

    • ACorrect. It's a sulfonamide combination antibiotic.
    • BIncorrect. That's Augmentin.
    • CIncorrect. That's an otic combination.
    • DIncorrect. That's an older pediatric combination.

Medications: FAQs

How much of the PTCE exam is Medications?

Medications is 35% of the PTCE exam by the official exam guide's weighting, which on a 90-question form works out to roughly 32 questions. The real exam's exact split varies by form.

What does the Medications domain cover?

The largest PTCE domain: brand and generic names, therapeutic classes, dosage forms and the safety information a technician must recognise.

How should I study Medications for PTCE?

Learn the top 200 drugs by class rather than alphabetically; questions often ask which drug belongs with which class or indication.

Where can I practise more Medications questions?

This page has 10 free Medications questions with answers. The ExamWize PTCE question bank has 207 questions in this domain. Every practice exam result breaks your score down by domain, and Review Mode re-drills the questions you missed.

Get Medications exam-ready

The full PTCE bank has 207 Medications questions. Timed practice exams match the real exam's length and domain weights, every result shows your score per domain, and Review Mode re-drills the questions you missed.

Not affiliated with PTCB; questions are original, written from the official exam outline, and never copied from the real exam.