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ExCPT Pharmacy Technician practice questions with answers

15 free practice questions for the Exam for the Certification of Pharmacy Technicians (ExCPT), spread across the exam's topics. Try each one, then open the answer to see why every option is right or wrong.

  1. Question 1 · Role, Responsibilities, and General Duties of the Pharmacy Technician

    According to CDC vaccine storage guidance, which setup is appropriate for storing vaccines that are labeled for refrigerated storage in a pharmacy?

    • AA purpose-built or pharmaceutical-grade refrigerator used only for vaccines and kept between 2°C and 8°C
    • BA dormitory-style combined refrigerator/freezer unit, as long as its thermometer reads between 2°C and 8°C
    • CA household refrigerator shared with staff food, as long as the vaccines are kept on a separate shelf
    • DThe freezer compartment of a household combination refrigerator/freezer, to extend the vaccines' shelf life
    Show answer and explanation

    Answer: A) A purpose-built or pharmaceutical-grade refrigerator used only for vaccines and kept between 2°C and 8°C

    CDC prefers dedicated purpose-built or pharmaceutical-grade units that keep refrigerated vaccines between 2°C and 8°C. Dormitory-style units, units shared with food, and household combination freezer compartments are not appropriate.

    • ACorrect. CDC prefers units that meet NSF/ANSI Standard 456, then purpose-built and pharmaceutical-grade units. Refrigerated vaccines must be kept between 2°C and 8°C (36°F and 46°F).
    • BIncorrect. CDC says never to use dormitory- or bar-style combined refrigerator/freezer units for vaccines, because they pose a significant risk of freezing vaccines.
    • CIncorrect. CDC says not to store food and beverages with vaccines. Opening the door often to get food can change the internal temperature.
    • DIncorrect. Refrigerated vaccines must not be frozen; for example, liquid vaccines with an aluminum adjuvant permanently lose potency. CDC also says never to use the freezer compartment of household combination units because of cold spots and temperature changes.
  2. Question 2 · Role, Responsibilities, and General Duties of the Pharmacy Technician

    In a hospital, which group decides which drugs are on the formulary?

    • AThe billing office, based on reimbursement rates
    • BThe Pharmacy and Therapeutics committee
    • CEach patient
    • DThe wholesaler
    Show answer and explanation

    Answer: B) The Pharmacy and Therapeutics committee

    • AIncorrect. The P&T committee decides.
    • BCorrect. It reviews safety, effectiveness and cost.
    • CIncorrect. The P&T committee decides.
    • DIncorrect. The P&T committee decides.
  3. Question 3 · Laws

    A pharmacy knowingly submits insurance claims for prescriptions that were never dispensed to patients. How is this activity classified?

    • AFraud
    • BAbuse
    • CWaste
    • DA clerical billing error
    Show answer and explanation

    Answer: A) Fraud

    Knowingly billing for prescriptions that were never dispensed is fraud. What separates fraud from abuse and waste is intent and knowledge.

    • ACorrect. Fraud is intentional deception or misrepresentation to get payment. CMS lists billing for services not furnished as an example of fraud.
    • BIncorrect. Abuse covers practices that go against sound medical, business, or fiscal practice but don't necessarily involve intentional deception. Knowingly billing for items never provided is deliberate, so it's fraud.
    • CIncorrect. Waste means misusing resources or running up unnecessary costs, such as overusing services. It isn't knowing misrepresentation on a claim.
    • DIncorrect. A clerical error is unintentional. This pharmacy acted knowingly, which shows the intent that makes it fraud.
  4. Question 4 · Laws

    Who licenses community pharmacies to operate?

    • AThe state board of pharmacy
    • BThe FDA
    • CThe wholesaler
    • DThe Joint Commission
    Show answer and explanation

    Answer: A) The state board of pharmacy

    • ACorrect. The DEA separately registers them for controlled substances.
    • BIncorrect. States license pharmacies.
    • CIncorrect. States license pharmacies.
    • DIncorrect. It accredits but doesn't license pharmacies.
  5. Question 5 · Drugs and Drug Therapy

    While picking up an atorvastatin refill, a patient mentions new, unexplained muscle pain and weakness. What is the most appropriate action for the pharmacy technician?

    • ASuggest an OTC pain reliever and tell the patient to keep taking the statin
    • BTell the patient to stop the statin and throw away the remaining tablets
    • CBring the complaint to the pharmacist's attention before the patient leaves
    • DDispense the refill and note the complaint for review at the next refill
    Show answer and explanation

    Answer: C) Bring the complaint to the pharmacist's attention before the patient leaves

    Unexplained muscle pain or weakness in a patient taking a statin can be a serious adverse effect. The technician should refer the patient to the pharmacist right away and should not give clinical advice.

    • AIncorrect. Recommending OTC therapy is clinical advice outside the technician's role, and it could hide a serious statin side effect that needs evaluation.
    • BIncorrect. Technicians do not give clinical advice, and patients are told not to stop atorvastatin without talking to their doctor.
    • CCorrect. Muscle pain, tenderness, or weakness on a statin can signal a serious muscle side effect that needs prompt attention, so the pharmacist should counsel the patient and contact the prescriber as needed.
    • DIncorrect. This symptom needs prompt attention. Waiting until the next refill could delay evaluation of a possibly serious adverse effect.
  6. Question 6 · Drugs and Drug Therapy

    What is the generic name of Glucotrol?

    • AGlyburide
    • BGlipizide
    • CMetformin
    • DGlimepiride
    Show answer and explanation

    Answer: B) Glipizide

    • AIncorrect. Glyburide has other brand names.
    • BCorrect. Glucotrol is glipizide, a sulfonylurea for type 2 diabetes.
    • CIncorrect. That is Glucophage.
    • DIncorrect. That is Amaryl.
  7. Question 7 · Dispensing Process

    A sig reads '1 tab po q4–6h prn pain.' What is the most tablets the patient could take in 24 hours?

    • A6
    • B4
    • C24
    • D10
    Show answer and explanation

    Answer: A) 6

    • ACorrect. Every 4 hours is 6 doses a day.
    • BIncorrect. That's every 6 hours.
    • CIncorrect. Doses are at least 4 hours apart.
    • DIncorrect. Every 4 hours is 6 doses.
  8. Question 8 · Dispensing Process

    How many milliliters are in 5 teaspoonfuls?

    • A15 mL
    • B25 mL
    • C50 mL
    • D5 mL
    Show answer and explanation

    Answer: B) 25 mL

    • AIncorrect. That is 3 teaspoons.
    • BCorrect. 1 teaspoon = 5 mL, so 5 teaspoons = 25 mL.
    • CIncorrect. That is 10 teaspoons.
    • DIncorrect. That is 1 teaspoon.
  9. Question 9 · Dispensing Process

    The prescription (Rx) number on a label is used to:

    • AIndicate the drug's DEA schedule on the label
    • BShow the drug's strength
    • CIdentify the prescription for refills
    • DGive the price
    Show answer and explanation

    Answer: C) Identify the prescription for refills

    • AIncorrect. It identifies the prescription.
    • BIncorrect. It identifies the prescription.
    • CCorrect. Patients can use it to request refills.
    • DIncorrect. It identifies the prescription.
  10. Question 10 · Dispensing Process

    A drug is dosed at 100 mg/m². The patient's body surface area is 1.5 m². What is the dose?

    • A66.7 mg
    • B150 mg
    • C101.5 mg
    • D1,500 mg
    Show answer and explanation

    Answer: B) 150 mg

    • AIncorrect. This divides instead of multiplying.
    • BCorrect. 100 mg/m² × 1.5 m² = 150 mg.
    • CIncorrect. This adds the values.
    • DIncorrect. This is ten times too high.
  11. Question 11 · Dispensing Process

    A claim rejects for 'quantity limit exceeded.' This usually means:

    • AThe amount exceeds what the plan allows
    • BThe patient isn't covered
    • CThe drug is a controlled substance that needs prior approval
    • DThe NDC is invalid
    Show answer and explanation

    Answer: A) The amount exceeds what the plan allows

    • ACorrect. Options include adjusting quantity or seeking an exception.
    • BIncorrect. It's a quantity rule.
    • CIncorrect. It's a plan quantity rule.
    • DIncorrect. It's a quantity rule.
  12. Question 12 · Dispensing Process

    Which syringe should be chosen to measure 2.4 mL accurately?

    • AA 3 mL syringe
    • BA 60 mL syringe
    • CA 1 mL syringe
    • DA 20 mL syringe
    Show answer and explanation

    Answer: A) A 3 mL syringe

    • ACorrect. Use the smallest syringe that holds the volume for best accuracy.
    • BIncorrect. Large syringes are less accurate for small volumes.
    • CIncorrect. It cannot hold 2.4 mL.
    • DIncorrect. It is less accurate for this volume.
  13. Question 13 · Dispensing Process

    An order calls for 20 mEq of potassium chloride. The solution contains 2 mEq/mL. How many milliliters are needed?

    • A22 mL
    • B40 mL
    • C5 mL
    • D10 mL
    Show answer and explanation

    Answer: D) 10 mL

    • AIncorrect. This adds the values.
    • BIncorrect. This multiplies instead of dividing.
    • CIncorrect. This does not match the figures.
    • DCorrect. 20 mEq ÷ 2 mEq/mL = 10 mL.
  14. Question 14 · Medication and Patient Safety and Quality Assurance

    FDA's Name Differentiation Project recommends tall man lettering for the opioid analgesic tramadol to set it apart from which look-alike/sound-alike drug name?

    • ATapentadol
    • BTrazodone
    • CTopiramate
    • DTizanidine
    Show answer and explanation

    Answer: B) Trazodone

    FDA's tall man lettering list includes traMADol/traZODone. The capital letters highlight how the two names differ, which helps prevent look-alike/sound-alike mix-ups during dispensing.

    • AIncorrect. Tapentadol is another opioid analgesic, but it is not the drug paired with tramadol on FDA's tall man lettering list.
    • BCorrect. FDA's list pairs tramadol with trazodone and recommends writing them as traMADol and traZODone.
    • CIncorrect. Topiramate starts with similar letters, but FDA does not pair it with tramadol on its tall man lettering list.
    • DIncorrect. Tizanidine is a muscle relaxant. It is not the drug paired with tramadol on FDA's tall man lettering list.
  15. Question 15 · Medication and Patient Safety and Quality Assurance

    A patient picking up a new prescription mentions having trouble understanding written health information. Which approach by the pharmacy best supports this patient's understanding of the directions?

    • AUse everyday words and short sentences, and state the most important instruction first
    • BHand over the full manufacturer package insert so the patient has every available detail
    • CUse the same clinical terms the prescriber wrote so the directions match the order exactly
    • DAsk the patient "Do you understand?" and treat a yes as confirmation of understanding
    Show answer and explanation

    Answer: A) Use everyday words and short sentences, and state the most important instruction first

    Plain language helps patients with low health literacy understand and use medication directions: everyday words, short sentences, and the key message first. Understanding is best confirmed with teach-back, not a yes/no question.

    • ACorrect. CDC plain-language guidance says to choose words the audience knows, limit each sentence to one idea, and put the most important message first. This helps patients with low health literacy understand directions the first time.
    • BIncorrect. Long, technical documents are harder for patients with low health literacy to use. More text does not mean better understanding, and key instructions can get lost.
    • CIncorrect. Clinical jargon makes information harder to understand. CDC recommends replacing jargon with everyday words.
    • DIncorrect. A yes/no answer does not confirm understanding. The teach-back method, where the patient explains the instructions in their own words, is the better way to check comprehension.

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Original questions written from the official exam outline. Not affiliated with NHA; never copied from the real exam.